Publications
Kaer Imaging System

NIR-II fluorescence

​​

Bădescu-Singureanu CC, Nizovtsev AS, Pecoraro VL, Petoud S, Eliseeva SV. Enabling Visible Light Sensitization of YbIII, NdIII and ErIII in Dimeric LnIII/GaIII Metallacrowns through Functionalization with RuII Complexes for NIR-II Multiplex Imaging. Angew Chem Int Ed Engl. 2024 Sep 17:e202416101. 

https://do.org/10.1002/anie.202416101

 

Kovalenko A, Eliseeva SV, Collet G, El Abdellaoui S, Natkunarajah S, Lerondel S, Guénée L, Besnard C, Petoud S. A Dual-Mode Near-Infrared Optical and Photoacoustic Imaging Agent Based on a Low Energy Absorbing Ytterbium Complex. J Am Chem Soc. 2024 May 15;146(19):12913-12918. 

https://doi.org/10.1021/jacs.4c03406

 

Le Guével X, Josserand V, Harki O, Baulin VA, Henry M, Briançon-Marjollet A. Real-time visualization of dextran extravasation in intermittent hypoxia mice using noninvasive SWIR imaging. Am J Physiol Heart Circ Physiol. 2024 Apr 1;326(4):H900-H906. 

https://doi.org/10.1152/ajpheart.00787.2023

 

He Y, Yu Z, Schomann T, Zhang H, Eich C, Cruz L. An EGF-modified PLGA-lanthanide nano platform for combined NIR-II cancer imaging and targeted drug delivery. bioRxiv. 2023 June 

https://doi.org/10.1101/2023.06.18.545497

​

Mu Q, Yao K, Syeda MZ, Zhang M, Cheng Q, Zhang Y, Sun R, Lu Y, Zhang H, Luo Z,
Huang H. Ligustrazine Nanoparticle Hitchhiking on Neutrophils for Enhanced Therapy of Cerebral Ischemia‐Reperfusion Injury. Advanced Science. 2023 Apr 20:2301348. doi: 10.1002/advs.202301348
https://doi.org/10.1002/advs.202301348

Thai QM, Kalot G, Venet C, Seguin J, Bocoum M, Mignet N, Ramaz F, Louchet-Chauvet A. In vivo ultrasound modulated optical tomography with a persistent spectral hole burning filter. Biomedical optics express. 2022 Dec 1;13(12):6484-96. doi:10.1364/BOE.475449
https://dx.doi.org/10.1364/BOE.475449

​

Kalot G, Godard A, Busser B, Bendellaa M, Dalonneau F, Paul C, Le Guével X, Josserand V, Coll JL, Denat F, Bodio E, Goze C, Gautier T, Sancey L. Lipoprotein interactions with water-soluble NIR-II emitting aza-BODIPYs boost the fluorescence signal and favor
selective tumor targeting. Biomater Sci. 2022 Sep 23. doi: 10.1039/d2bm01271e
https://dx.doi.org/10.1039/d2bm01271e

​

Yao K, Mu Q, Zhang Y, Cheng Q, Cheng X, Liu X, Luo C, Li C, Cai S, Luo Z, Zhu X, Tang, L. Hesperetin Nanoparticle Targeting Neutrophils for Enhanced TBI Therapy. Advanced Functional Materials, 2205787. 2022. doi: 10.1002/adfm.202205787

https://dx.doi.org/10.1002/adfm.202205787

​

Rodríguez-Luna MR, Okamoto N, Al-Taher M, Keller DS, Cinelli L, Hoskere Ashoka A, Klymchenko AS, Marescaux J, Diana M. In Vivo Imaging Evaluation of Fluorescence Intensity at Tail Emission of Near-Infrared-I (NIR-I) Fluorophores in a Porcine Model. Life (Basel). 2022 Jul 27;12(8):1123. doi: 10.3390/life12081123

https://dx.doi.org/10.3390/life12081123

​

Yu Z, He Y, Schomann T, Wu K, Hao Y, Suidgeest E, Zhang H, Eich C, Cruz LJ. Achieving Effective Multimodal Imaging with Rare-Earth Ion-Doped CaF2 Nanoparticles. Pharmaceutics. 2022 Apr 11;14(4):840. doi: 10.3390/pharmaceutics14040840

https://dx.doi.org/10.3390/pharmaceutics14040840

​

Liu Q, Zhong Y, Su Y, Zhao L, Peng J. Real-Time Imaging of Hepatic Inflammation Using Hydrogen Sulfide-Activatable Second Near-Infrared Luminescent Nanoprobes. Nano Lett. 2021 Jun 9;21(11):4606-4614. doi: 10.1021/acs.nanolett.1c00548. Epub 2021 May 20. PMID: 34014668.

https://dx.doi.org/10.1021/acs.nanolett.1c00548

​​

​​

Near infrared fluorescence

​​

Holm-Weber T, Mohanakumar S, Helt TW, Borgwardt L, Borgwardt L, Juul K, Christensen VB, Hjortdal VE. Lymphatic magnetic resonance imaging abnormalities in children with repaired tetralogy of Fallot. Cardiol Young. 2024 Oct 10:1-7

https://doi.org/10.1017/S1047951124025435

 

Hautiere M, Vivier D, Dorval P, Pineau D, Kereselidze D, Denis C, Herbet A, Costa N, Bernhard C, Goncalves V, Selingue E, Larrat B, Dancer PA, Hugnot JP, Boquet D, Truillet C, Denat F. Preoperative PET imaging and fluorescence-guided surgery of human glioblastoma using dual-labeled antibody targeting ETA receptors in a preclinical mouse model: A theranostic approach. Theranostics 2024; 14(16):6268-6280

https://www.thno.org/v14p6268.htm

 

Holm-Weber T, Skov F, Mohanakumar S, Thorup L, Riis T, Christensen MB, Sonne DP, Jensen PB, Bødtkjer DB, Hjortdal VE. Octreotide improves human lymphatic fluid transport a translational trial. Eur J Cardiothorac Surg. 2024 Jan 2;65(1):ezad380. 

https://doi.org/10.1093/ejcts/ezad380

 

Heremans J, Maximilian Awad R, Bridoux J, Ertveldt T, Caveliers V, Madder A, Hoogenboom R, Devoogdt N, Ballet S, Hernot S, Breckpot K, Martin C. Sustained release of a human PD-L1 single-domain antibody using peptide-based hydrogels. Eur J Pharm Biopharm. 2024 Mar;196:114183.

https://doi.org/10.1016/j.ejpb.2024.114183

 

Privat M, Massot A, Hermetet F, Al Sabea H, Racoeur C, Mabrouk N, Cordonnier M, Moreau M, Collin B, Bettaieb A, Denat F, Bodio E, Bellaye PS, Goze C, Paul C. Development of an Immuno-SPECT/Fluorescent Bimodal Tracer Targeting Human or Murine PD-L1 on Preclinical Models. J Med Chem. 2024 Feb 8;67(3):2188-2201

https://doi.org/10.1021/acs.jmedchem.3c02120

​

​Vivier D, Hautière M, Pineau D, Dancer PA, Herbet A, Hugnot JP, Bernhard C, Goncalves V, Truillet C, Boquet D, Denat F. Synthesis and Preclinical Fluorescence Imaging of Dually Functionalized Antibody Conjugates Targeting Endothelin Receptor-Positive Tumors. Bioconjugate Chemistry. 2023 Nov 6.

https://doi.org/10.1021/acs.bioconjchem.3c00445

​

Holm-Weber T, Kristensen RE, Mohanakumar S, Hjortdal VE. Gravity and lymphodynamics. Physiol Rep. 2022 May. doi: 10.14814/phy2.15289

https://dx.doi.org/10.14814/phy2.15289

​

Privat M, Bellaye PS, Lescure R, Massot A, Baffroy O, Moreau M, Racoeur C, Marcion G, Denat F, Bettaieb A, Collin B, Bodio E, Paul C, Goze C. Development of an Easily Bioconjugatable Water-Soluble Single-Photon Emission-Computed Tomography/Optical Imaging Bimodal Imaging Probe Based on the aza-BODIPY Fluorophore. J Med Chem. 2021 Aug 2. doi: 10.1021/acs.jmedchem.1c00450. Epub ahead of print. PMID: 34338511.

https://doi.org/10.1021/acs.jmedchem.1c00450

​​

Debie P, Declerck NB, van Willigen D, Huygen CM, De Sloovere B, Mateusiak L, Bridoux J, Puttemans J, Devoogdt N, van Leeuwen FWB, Hernot S. The Design and Preclinical Evaluation of a Single-Label Bimodal Nanobody Tracer for Image-Guided Surgery. Biomolecules. 2021 Feb 26;11(3):360. doi: 10.3390/biom11030360. PMID: 33652977; PMCID: PMC7996797.

https://dx.doi.org/10.3390%2Fbiom11030360

​​

Hu Q,Wang K, Qiu L. 6-Aminocaproic acid as a linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green. Colloids Surf B Biointerfaces. 2021 Jan;197:111372. doi: 10.1016/j.colsurfb.2020.111372.

https://dx.doi.org/10.1016/j.colsurfb.2020.111372

​​

Renard E, Dancer PA, Portal C, Denat F, Prignon A, Goncalves V. Design of Bimodal Ligands of Neurotensin Receptor 1 for Positron Emission Tomography Imaging and Fluorescence-Guided Surgery of Pancreatic Cancer. J Med Chem. 2020 Mar 12;63(5):2426-2433. doi: 10.1021/acs.jmedchem.9b01407. Epub 2020 Jan 2. PMID: 31855417.

https://dx.doi.org/10.1021/acs.jmedchem.9b01407​

​